Polling stations were ransacked, ballot boxes were stuffed by police and observers were prevented from overseeing the integrity of the vote, according to several witnesses.
Those arrested on Thursday were part of a march by roughly 100 women to the Supreme Court where they were planning to appeal for the results to be nullified.
Armed police dispersed them, and 12 of the protesters were arrested for unspecified crimes.
Opposition parties in the coup-prone Indian Ocean country have opted not to appeal the vote's outcome but called instead for new polls to be held as soon as possible.
Interior Minister Mohamed "Kiki" Daoudou has dismissed criticism of the polls' conduct and said that "it's not the street which rules the country."
For months the opposition has accused Azali of behaving like a dictator.
Azali staged the poll after Comorans voted in a referendum, boycotted by the opposition, to support the extension of presidential mandates from one five-year term to two.
He could theoretically rule until 2029, critics say, and several opposition figures were arrested around the time of the referendum.
The change upset a fragile balance of power established in 2001 that sought to end separatist crises on Anjouan and Moheli islands, and halt an endless cycle of coups.
Source: AFP