TEHRAN, August 25 - As the U.S. opioid addiction epidemic widened, the federal Drug Enforcement Agency, or DEA, placed the prescription painkillers in a tougher-to-refill category.
TEHRAN, Young Journalists Club (YJC) -As the U.S. opioid addiction epidemic widened, the federal Drug Enforcement Agency, or DEA, placed the prescription painkillers in a tougher-to-refill category.
Many states also mandated monitoring programs to spot overprescribing by doctors.
But two new studies suggest these steps, while well-intentioned, may have led to more opioids -- not fewer -- being given to patients by surgeons after routine operations.
In the case of the DEA's 2014 action to move opioid painkillers to a more restricted class, this "may inadvertently motivate surgeons to prescribe greater amounts to ensure adequate pain treatment," said Dr. Jennifer Waljee, lead author of one of the studies. She codirects the Michigan Opioid Prescribing Engagement Network.
Her team believes that once prescription refills became tougher under the new DEA rules, surgeons who worried about a patient's longer-term pain control simply ordered a larger number of pills so the patient had a "stockpile" of opioids to use at home.
Opioid use for postoperative pain control is thought to be a major "gateway" to addiction, experts note.
The findings made sense to one physician.
While more prescribing after a tightening of rules seems "counterintuitive," Dr. Joseph Conigliaro said he "agrees with the findings.
"In the case of someone having surgery, they are in acute pain, meaning it shouldn't last long," said Conigliaro, who is chief of internal medicine at Northwell Health in Lake Success, N.Y.
"But because there are limits on prescriptions postsurgery, sometimes physicians can prescribe someone twice to four times as much to ensure they will ultimately have what they need," explained Conigliaro, who wasn't involved in the new study.
In their research, Waljee and her colleagues tracked opioid prescription patterns before and after the DEA's new rule, which moved the opioid hydrocodone (Vicodin) from schedule III to the more restrictive schedule II.
The change meant that doctors could now only prescribe a 90-day supply, and couldn't prescribe over the telephone or by fax.
Data on nearly 22,000 privately insured patients in Michigan -- all of whom underwent common elective surgeries -- found that far from hydrocodone prescription rates dropping, the number of prescriptions actually rose after the new rule.
Although there was a reduction in the prescription refill rate, there was an overall average 7-tablet-per-patient rise in hydrocodone prescribing after the DEA change, Waljee's group noted.
Why the unexpected trend?
"Our main thought was that since surgeons were more limited in their ability to prescribe extra pain medications after the patient left the hospital, they prescribed more up front to avoid the risk of patients running out," said study co-author Dr. Joe Habbouche. He's a surgery resident at Michigan Medicine, the academic medical center at the University of Michigan.
In a second study, researchers at Dartmouth-Hitchcock Medical Center in Lebanon, N.H., looked at changes in opioid prescribing after New Hampshire mandated "prescription drug monitoring programs." These programs exist in many states and track doctors' opioid prescribing patterns.
The New Hampshire program went into effect Jan. 1, 2017, and the Dartmouth team looked at opioid prescription patterns for more than 1,000 patients who'd undergone an elective surgery in the six months before or after the change.
Researchers led by the hospital's Dr. Richard Barth found that "the percentage of patients prescribed opioids after surgery did not decrease significantly" after the monitoring program came into effect.
In fact, the average number of opioid pills dispensed after surgery was already decreasing before the implementation of the new program, but that decline actually slowed "in the six months after the legislation," Barth's group reported.
Source:UPI
Your Comment